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April.!
Distinguishing between Inclusion Body Hepatitis (IBH) and mycotoxicosis in poultry involves assessing both clinical history and specific pathological lesions. IBH is a viral disease caused by Fowl Adenovirus, often marked by sudden high mortality in young broilers (3–7 weeks) and a swollen, friable, yellowish liver with distinctive intranuclear inclusion bodies visible under a microscope. Conversely, mycotoxicosis (particularly from Aflatoxins or T-2 toxins) is a non-infectious condition resulting from contaminated feed, typically leading to chronic issues like oral crusts, gizzard erosion, and pale, fatty livers with bile duct hyperplasia rather than inclusions. Although both conditions cause hepatomegaly and icterus, IBH tends to present with more acute, hemorrhagic-like lesions in the liver and muscles. In contrast, mycotoxicosis usually shows dose-dependent regression of the Bursa of Fabricius and lacks horizontal transmission among birds.
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