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Drug administration
Posted by Babafemi Adejinmi on March 10, 2025 at 3:22 pmWhich is a better more effective route of drug administration, oral or IM
AFOLABI SUNDAY TUNDE replied 1 year, 3 months ago 16 Members · 18 Replies -
18 Replies
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Oral can be handled by any person, IM requires skill
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The effectiveness of drug administration depends on the drug type and desired effect.
- <strong data-start=”914″ data-end=”930″>IM Route is better when <strong data-start=”946″ data-end=”966″>rapid absorption is needed, such as in emergencies or for drugs that are poorly absorbed orally.
- <strong data-start=”1051″ data-end=”1074″>Oral Administration is better for long term therapy.
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Please follow manufacturer guidelines regarding route of Drug administration.you can find instructions written on label or as per recommendation given by Veterinarians.
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good article.indeed,AE is a devastating diseaese if proper vaccination is not carried out in breeders
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Avian Encephalomyelitis
AE or Epidemic Tremor
Cause
Avian Encephalomyelitis (AE) is caused by an enterovirus belonging to
the picornavirus group.
Transmission
Egg transmission is the major route of transmission of AE virus. Infected
breeders will show a drop in egg production and in hatchability.
Infected chickens that hatch will show clinical signs of the disease and
spread the infection in the incubator to other newly hatched
susceptible chickens. Young chickens can also be infected on the farm.
The incubation period varies from 5 to 14 days depending on the route
of infection.
Species affected
Primarily, chickens are susceptible to AE, but turkeys and pheasants
have been reported as natural hosts.Avian Encephalomyelitis
AE or Epidemic Tremor
Cause
Avian Encephalomyelitis (AE) is caused by an enterovirus belonging to
the picornavirus group.
Transmission
Egg transmission is the major route of transmission of AE virus. Infected
breeders will show a drop in egg production and in hatchability.
Infected chickens that hatch will show clinical signs of the disease and
spread the infection in the incubator to other newly hatched
susceptible chickens. Young chickens can also be infected on the farm.
The incubation period varies from 5 to 14 days depending on the route
of infection.
Species affected
Primarily, chickens are susceptible to AE, but turkeys and pheasants
have been reported as natural hosts.Clinical signs
Clinical tremors and increased mortality in young chickens, together with
a drop in production and hatchability in the breeders or egg production
drop in layers are signs related to AE.
The disease is mainly seen in young chickens, between 1 and 3 weeks of
age. Affected chickens sit on their hocks, do not move well, and many fall
on their sides. A fine, rapid trembling of the head and neck can be seen,
but especially felt when affected chickens are held in the hand. In laying
and breeding flocks, AE virus infection causes a marked drop in egg
production which returns to normal in about 2-3 weeks. Mortality in
naturally infected chickens varies and can be as high as 75%.
Diagnosis
Clinical tremors in young chickens, together with a drop in production
and hatchability in the breeders or production drop in layers are
indicative for AE infection. Chickens will not have gross lesions, but
histological examination of brain, proventriculus and pancreas reveals
typical lesions of AE. This will also differentiate the diagnosis of AE
from encephalomalacia (Vitamin E deficiency, crazy chicken disease).
Laboratory testing of blood serum from breeder flocks for the presence
of antibodies, or their hatching eggs, can determine if an infection
occurred.
Treatment
There is no effective treatment for AE.Clinical signs
Clinical tremors and increased mortality in young chickens, together with
a drop in production and hatchability in the breeders or egg production
drop in layers are signs related to AE.
The disease is mainly seen in young chickens, between 1 and 3 weeks of
age. Affected chickens sit on their hocks, do not move well, and many fall
on their sides. A fine, rapid trembling of the head and neck can be seen,
but especially felt when affected chickens are held in the hand. In laying
and breeding flocks, AE virus infection causes a marked drop in egg
production which returns to normal in about 2-3 weeks. Mortality in
naturally infected chickens varies and can be as high as 75%.
Diagnosis
Clinical tremors in young chickens, together with a drop in production
and hatchability in the breeders or production drop in layers are
indicative for AE infection. Chickens will not have gross lesions, but
histological examination of brain, proventriculus and pancreas reveals
typical lesions of AE. This will also differentiate the diagnosis of AE
from encephalomalacia (Vitamin E deficiency, crazy chicken disease).
Laboratory testing of blood serum from breeder flocks for the presence
of antibodies, or their hatching eggs, can determine if an infection
occurred.
Treatment
There is no effective treatment for AE.Control
Preventive vaccination of breeder pullets and layer pullets with live
AE vaccine before egg production is the only effective means of AE
control. If a breeder flock has not been, or has been inadequately or
not vaccinated against AE and an outbreak occurs, it is advisable to
stop hatching eggs from the flock for several weeks until the breeders
have acquired immunity and no longer transmit AE virus through their
eggs.
egg production %Control
Preventive vaccination of breeder pullets and layer pullets with live
AE vaccine before egg production is the only effective means of AE
control. If a breeder flock has not been, or has been inadequately or
not vaccinated against AE and an outbreak occurs, it is advisable to
stop hatching eggs from the flock for several weeks until the breeders
have acquired immunity and no longer transmit AE virus through their
eggs.
egg production % -
Oral is best for large-scale treatment and preventive care WHILE
IM is better for fast action and individual treatment.
The choice depends on the drug, disease, and production system.
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Administration to be followed as per manufacturers instructions
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Neither one is better than the other, both routes are effective. Medications must be administered according to the instructions in the label. IM drugs are not formulated to be offered orally and vice versa. Drug manufactures test different routes of administration and often select the most effective for their product.
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