IBH vs mycotoxin

[Dr. Mahmoud Elnakeeb]

Nice

[Dr. Mahmoud Elnakeeb]

Differentiating between Inclusion Body Hepatitis (IBH) and mycotoxicosis in poultry requires evaluating both clinical history and specific pathological lesions. IBH is a viral infection caused by Fowl Adenovirus, typically characterized by sudden high mortality in young broilers (3–7 weeks) and a swollen, friable, yellowish liver with distinct intranuclear inclusion bodies visible under microscopic examination. In contrast, mycotoxicosis (specifically from Aflatoxins or T-2 toxins) is a non-infectious condition resulting from contaminated feed, often causing more chronic issues like oral crusts, gizzard erosion, and pale, fatty livers with bile duct hyperplasia rather than inclusions. While both cause hepatomegaly and icterus, IBH presents with more acute hemophilic-like hemorrhages on the liver and muscles, whereas mycotoxicosis typically shows a dose-dependent regression of the Bursa of Fabricius and a lack of horizontal transmission between birds.